Hereditary spastic paraplegia (HSP) is a degenerative disease of nervous
system. How to manage the HSP? Now we are talking about this topic.
I. Goal for the Treatment of HSP
The goal for the treatment of HSP is to relieve the high muscle tone, improve
the motor dysfunction, inhibit the progression and prevent the relevant
complications.
II. Clinical manifestation:
HSP occurs most often in childhood and puberty, and other ages are also
available. Male is more likely to be affected. Usually people have positive
hereditary history for this disease.
How to manage the HSP? People with HSP will suffer from a progressive spastic
myasthenia in both their lower limbs, high muscle tone, sthenic tendon reflex
activity, knee and ankle clonus, X-walk and so on. The complications may include
optic atrophy, pigmentary degeneration of retina, extrapyramidal system
symptoms, cerebellar ataxia, disturbance of sensation, mental retardation,
epicophosis (deaf), amyotrophia, autonomic nervous dysfunction. Talipes may
occur as well.
III. Auxiliary examination:
How to manage the HSP? Some indicators may show the category and severity of
the disease, which provides enough information for the further treatment.
1. SEP (Somatosensory Evoked Potential)
SEP shows nerve fiber and corticospinal tract conduction velocity decreases
in lower limbs of HSP patients.
2. EMG (electromyogram)
Denervation change may be found in these HSP patients, but peripheral nerve
conduction velocity keeps normal.
3. MRI (Magnetic Resonance Imaging)
Usually the MRI shows normal in the brain. But for some special cases, people
may show cerebral atrophy, cerebellar atrophy or amyelotrophy (spinal cord
atrophy) in their cervical and thoracic vertebra.
IV. Treatment for HSP:
How to manage the HSP? In clinic, Stem Cell Transplantation treatment for HSP turns out much better
effect than conventional therapies, especially for these who were found
earlier.
1. Conventional therapies
Currently, there is no effective treatment for HSP, and conventional
therapies include drugs, surgery to lengthen heel tendon, massage, physio,
acupuncture and moxibustion and so on. There therapies can improve the spasm and
motor dysfunction, but can’t cure the disease fundamentally.
2. SCT treatment for HSP
How to manage the HSP? Stem cell transplantation (SCT) treatment for HSP
shows good effect in clinic. Stem cell can not only fix and replace the impaired
nerves and rebuild the neural circuit, but also secrete cell growth factors
which will activate and nourish the impaired nerve factors.
In stem cell center, we have already treated more than 7,000 patients with
cerebral palsy, cerebellar ataxia and cerebellar atrophy, and the effective rate
is more than 86.9%.
How to manage the HSP? SCT treatment turns out a potential cure for HSP in
clinic, find more details, contact us at stemcellprc@gmail.com.
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